{"id":313,"date":"2015-01-23T12:39:23","date_gmt":"2015-01-23T14:39:23","guid":{"rendered":"http:\/\/www.planetaw.com.br\/temp\/sbg\/?p=313"},"modified":"2019-06-24T15:59:15","modified_gmt":"2019-06-24T18:59:15","slug":"tamanho-disco-optico-vs-progressao-funcional-no-glaucoma-de-pressao-normal","status":"publish","type":"post","link":"https:\/\/www.sbglaucoma.org.br\/medico\/tamanho-disco-optico-vs-progressao-funcional-no-glaucoma-de-pressao-normal\/","title":{"rendered":"TAMANHO DISCO \u00d3PTICO VS. PROGRESS\u00c3O FUNCIONAL NO GLAUCOMA DE PRESS\u00c3O NORMAL"},"content":{"rendered":"
\n
\"\"\"Daniela-L-M-Junqueira\"Comentarios de Tiago Prata e Dra Daniela L M Junqueira sobre:<\/strong>
\nRef.: Optic disc size and progression of visual field damage in patients with normal tension glaucoma.<\/strong>
\nHayamizu F, Yamazaki Y, Nakagami T, Mizuki K.
\nClin Ophthalmol. 2013<\/strong>
\n<\/span><\/span><\/div>\n
E\"\"ditor Associado<\/strong>
\nTiago Prata<\/strong>
\n<\/span><\/span><\/div>\n<\/div>\n

Determinadas caracter\u00edsticas da cabe\u00e7a do nervo \u00f3ptico, principalmente relacionadas \u00e0 lamina cribrosa e esclera peripapilar, podem estar associadas com a susceptibilidade ao glaucoma.<\/span> Estudos pr\u00e9vios sugerem que discos \u00f3pticos grandes podem ter caracter\u00edsticas biomec\u00e2nicas mais suscept\u00edveis \u00e0 neuropatia \u00f3ptica glaucomatosa. Este estudo foi desenhado para responder a seguinte pergunta: existe rela\u00e7\u00e3o entre o tamanho do disco \u00f3ptico e a progress\u00e3o funcional em olhos com glaucoma de press\u00e3o normal (GPN)?<\/p>\n

Para isso, foram analisados 82 pacientes com GPN (tratados), acompanhados por pelo menos quatro anos, com acuidade visual m\u00ednima de 20\/25 durante todo o estudo, e subdivididos em dois grupos de acordo com a \u00e1rea do disco \u00f3ptico (conforme aferido em imagens do HRT). Utilizando os crit\u00e9rios de progress\u00e3o funcional do CNTGS, os autores observaram que pacientes com GPN e disco \u00f3ptico grande apresentaram maior frequ\u00eancia de progress\u00e3o no campo visual quando comparados com aqueles com disco \u00f3ptico pequeno (26\/38 [68%] vs. 17\/44 [39%]; p=0.009).<\/span><\/p>\n

Demais fatores associados \u00e0 progress\u00e3o funcional foram a ocorr\u00eancia de hemorragia de disco e a magnitude de redu\u00e7\u00e3o da press\u00e3o intraocular.<\/span> Entretanto, o tamanho do disco \u00f3ptico representou um fator de risco independente mesmo na an\u00e1lise multivariada. Os resultados deste estudo retrospectivo sugerem que o tamanho do disco seja relevante na avalia\u00e7\u00e3o do risco de progress\u00e3o do GPN. Estudos adicionais, preferencialmente prospectivos, s\u00e3o necess\u00e1rios para confirmar essas informa\u00e7\u00f5es.<\/span><\/p>\n

\n
\n

Resumo deste artigo<\/h3>\n
\n
\n
\n

Clin Ophthalmol.<\/em> 2013;7:807-13. doi: 10.2147\/OPTH.S42468. Epub 2013 May 3.
\nOptic disc size and progression of visual field damage in patients with normal-tension glaucoma.<\/strong>
\nHayamizu F, Yamazaki Y, Nakagami T, Mizuki K.<\/p>\n

Author information<\/strong><\/p>\n

Abstract<\/strong><\/p>\n

PURPOSE:<\/strong>
\nOur goal was to evaluate the influence of optic disc size on the progression of visual field damage in patients with normal-tension glaucoma (NTG).<\/p>\n

SUBJECTS AND METHODS:<\/strong>
\nEighty-two eyes of 82 NTG patients who had been receiving topical antiglaucoma medications and followed-up for more than 4 years were enrolled in this study. The patients were allocated to two groups, according to the mean size of their optic discs. The data were analyzed using regression analysis, based on the Cox proportional hazard model.<\/p>\n

RESULTS:<\/strong>
\nThe probability of visual field stability was significantly lower in eyes with large discs than in those with small discs (log rank test, P = 0.007). Progression of visual field damage was significantly associated with the optic disc area (hazard ratio [HR]: 1.812, P = 0.018), occurrence of disc hemorrhage (HR: 2.116, P = 0.028), and intraocular pressure reduction ratio (HR: 0.957, P = 0.014).<\/p>\n

CONCLUSION:<\/strong>
\nThe optic disc area correlates with progression of visual field damage in patients with NTG.<\/p>\n

KEYWORDS:<\/strong>
\nCox proportional hazards model, Kaplan\u2013Meier life-table analysis, disc hemorrhage, disc size, intraocular pressure<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Comentarios de Tiago Prata e Dra Daniela L M Junqueira sobre: Ref.: Optic disc size and progression of visual field damage in patients with normal tension glaucoma. Hayamizu F, Yamazaki Y, Nakagami T, Mizuki K. Clin Ophthalmol. 2013 Editor Associado Tiago Prata Determinadas caracter\u00edsticas da cabe\u00e7a do nervo \u00f3ptico, principalmente relacionadas \u00e0 lamina cribrosa e […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_joinchat":[],"footnotes":""},"categories":[1],"tags":[],"class_list":["post-313","post","type-post","status-publish","format-standard","hentry","category-sem-categoria"],"acf":[],"yoast_head":"\nTAMANHO DISCO \u00d3PTICO VS. 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